What is Multiple Drug Sensitivity?
Multiple Drug Sensitivity (MDR1) is a genetic mutation that affects how a dog processes certain medications. Affected dogs can suffer severe reactions to common drugs like ivermectin and certain anaesthetics.
How is MDR1 Diagnosed?
A DNA test can detect the MDR1 mutation. Testing is recommended for herding breeds like Collies and Australian Shepherds, as they are most commonly affected.
Managing Drug Sensitivity in Dogs
Dogs with MDR1 require special medication protocols. Vets adjust drug dosages or choose alternative treatments to prevent toxic reactions.
